Chemotaxonomy and Antibacterial Activity of the Extracts and Chemical Constituents of Psychotria succulenta Hiern. (Rubiaceae)
Table 1
Antibacterial activity of the extracts and some isolated compounds from P. succulenta seeds.
Samples
Parameters
Bacterial species
Pseudomonas aeruginosa
Staphylococcus aureus
Escherichia coli
Klebsiella pneumoniae
EtOH extract
MIC/MBC
128/256
-/-
64/128
32/64
EtOAc extract
MIC/MBC
64/256
64/128
-/-
64/128
n-BuOH extract
MIC/MBC
32/64
32/128
64/128
32/128
1
MIC/MBC
128/128
-/-
32/128
128/128
2
MIC/MBC
64/64
128/-
128/128
32/64
3
MIC/MBC
64/128
64/128
-/-
128/128
4
MIC/MBC
64/-
64/-
-/-
-/-
5
MIC/MBC
64/128
32/64
64/64
32/64
6
MIC/MBC
128/-
-/-
-/-
128/-
9
MIC/MBC
32/64
16/32
64/128
16/32
10
MIC/MBC
128/-
-/-
-/-
64/-
11
MIC/MBC
128/-
128/-
-/-
128/-
12
MIC/MBC
64/-
-/-
-/-
32/-
13
MIC/MBC
128/-
128/-
64/-
-/-
Ciprofloxacine
MIC/MBC
2/4
8/16
8/16
8/16
MIC: minimum inhibitory concentration; MBC: minimum bactericidal concentration; MIC and MBC in μg/mL; -: not active at concentration up to 256 μg/mL for the compounds and 2048 μg/mL for the extracts.
