Clinical Prediction Nomograms to Assess Overall Survival and Disease-Specific Survival of Patients with Salivary Gland Adenoid Cystic Carcinoma

Table 1

Characteristics and survival rate of patients with salivary gland adenoid cystic carcinoma.

Number of patients () (%)			Overall survival (%)				Disease-specific survival (%)
Characteristic	Frequency	Percent (%)	3-year	5-year	10-year	Last follow-up	3-year	5-year	10-year	Last follow-up
Age
<40 years	116	17.6	90.5	88.8	85.3	85.3	90.5	88.8	85.3	85.3
40-49 years	116	17.6	87.1	81.0	78.6	77.6	89.7	83.6	79.3	79.3
50-59 years	138	21.0	89.1	86.2	83.3	82.6	89.1	86.2	84.1	84.1
60-69 years	136	20.7	82.4	77.2	73.8	72.8	86.8	83.1	80.1	80.1
≥70 years	152	23.1	79.6	73.0	67.1	65.8	83.6	78.3	76.3	75.7
Gender
Female	379	57.6	86.0	81.5	77.6	77.0	87.6	83.6	81.3	81.0
Male	279	42.4	84.6	79.9	75.6	75.3	87.8	83.9	80.3	80.3
Race
White	503	76.4	86.1	81.1	76.7	76.3	88.7	84.5	81.7	81.7
Black	71	10.8	81.7	81.7	76.1	76.1	84.5	84.5	78.9	78.9
Other	84	12.8	84.5	78.6	77.4	76.2	84.5	78.6	77.4	76.2
Marital status
Married	380	57.7	85.8	81.6	77.1	76.6	88.2	84.7	80.8	80.5
Single	129	19.6	86.8	82.9	79.8	79.1	88.4	85.3	82.2	82.2
Separated	11	1.7	81.8	72.7	72.7	72.7	81.8	72.7	72.7	72.7
Divorced	58	8.8	87.9	86.2	81.0	81.0	89.7	87.9	87.9	87.9
Widowed	53	8.1	77.4	73.6	67.9	67.9	81.1	77.4	77.4	77.4
Unknown	27	4.1	85.2	66.7	66.7	66.7	88.9	70.4	70.4	70.4
Primary site of tumor
Parotid gland	199	30.2	87.4	82.9	79.9	79.9	88.4	84.4	82.4	82.4
Palate	104	15.8	89.4	85.6	82.7	81.7	93.3	91.3	91.3	90.4
Other major salivary glands	219	33.3	84.0	77.6	73,5	72.6	85.8	79.9	76.7	76.7
Other minor salivary glands	136	20.7	81.6	79.4	72.8	72.8	85.3	83.1	77.2	77.2
AJCC stage
I	171	26.0	96.5	94.7	91.2	90.1	97.7	96.5	94.7	94.2
II	150	22.8	94.7	90.7	86.0	84.7	96.7	94.0	91.3	91.3
III	119	18.1	86.6	82.4	78.2	78.2	89.1	84.9	80.7	80.7
IVA	139	21.1	77.0	69.8	64.0	64.0	80.6	73.4	69.1	69.1
IVB	29	4.4	58.6	48.3	48.3	48.3	65.5	58.6	58.6	58.6
IVC	50	7.6	56.0	50.0	48.0	48.0	56.0	50.0	48.0	48.0
T stage
T1	190	28.9	92.6	90.5	87.4	86.8	93.7	92.1	90.5	90.0
T2	179	27.2	93.9	89.9	86.0	84.9	95.5	92.7	90.5	90.5
T3	126	19.1	78.6	72.2	66.7	66.7	81.7	75.4	69.0	69.0
T4a	132	20.1	77.3	71.2	65.1	65.9	80.3	74.2	71.2	71.2
T4b	31	4.7	54.8	45.2	45.2	45.2	61.3	54.8	54.8	54.8
N stage
N0	533	81.0	89.5	84.8	80.9	80.3	91.9	88.0	85.4	85.2
N1	70	10.6	80.0	78.6	74.3	74.3	80.0	78.6	75.7	75.7
N2a	4	0.6	50.0	50.0	50.0	50.0	50.0	50.0	50.0	50.0
N2b	44	6.7	52.3	43.2	40.9	40.9	56.8	47.7	43.2	43.2
N2c+N3	7	1.1	57.1	57.1	28.6	28.6	57.1	57.1	42.9	42.9
M stage
M0	608	92.4	87.8	83.4	79.1	78.6	90.3	86.5	83.6	83.4
M1	50	7.6	56.0	50.0	48.0	48.0	56.0	50.0	48.0	48.0
Grade
Low-grade	161	24.5	95.7	94.4	90.7	90.1	96.3	95.7	93.2	92.5
Intermediate-grade	309	46.9	92.6	88.3	84.1	83.5	94.1	90.9	88.3	88.3
High-grade	113	17.2	63.7	55.8	54.0	54.0	68.1	61.1	58.4	58.4
High-grade transformation	75	11.4	66.7	58.7	50.7	50.7	72.0	62.7	57.3	57.3
Surgery
No	29	4.4	44.8	41.4	34.5	34.5	44.8	44.8	37.9	37.9
Yes	629	95.6	87.3	82.7	82.7	78.2	89.7	85.5	82.8	82.7
Radiation
No	169	25.7	87.6	82.2	76.9	76.3	91.7	87.0	84.6	84.0
Yes	489	74.3	84.7	80.4	76.7	76.3	86.3	82.6	79.6	79.6
Chemotherapy
No	586	89.1	88.2	83.6	79.4	78.8	90.4	86.5	83.8	83.6
Yes	72	10.9	62.5	58.3	55.6	55.6	65.3	61.1	56.9	56.9
Neck dissection
No	295	44.8	86.8	82.0	79.3	79.0	88.8	84.7	83.7	83.4
Yes	363	55.2	84.3	79.9	74.7	74.1	86.8	82.9	78.5	78.5