Research Article

Comparison of Different Machine Learning Models in Prediction of Postirradiation Recurrence in Prostate Carcinoma Patients

Table 4

The value of nadir PSA, time to nadir PSA, PSA doubling time, PSA velocity, and PSA in the moment of disease reevaluation, in prediction of disease progression.

CharacteristicThe presence/absence of disease progression – training group
PresenceAbsenceWilcoxon rank sum test

Nadir PSA (ROC cut-off value)
  ≤0.309520 (37.0%)17 (68.0%)
  >0.309534 (63.0%)8 (32.0%)
Time to nadir PSA (ROC cut-off value)
  ≤6.536 (66.7%)5 (20.0%)
  >6.518 (33.3%)20 (80.0%)
PSA doubling time (ROC cut-off value)
  ≤5.0543 (79.6%)4 (16.0%)
  >5.0511 (20.4%)21 (84.0%)
PSA velocity (ROC cut-off value)
  ≤0.5515 (27.8%)23 (92.0%)
  >0.5539 (72.2%)2 (8.0%)
PSA in the moment of disease reevaluation (ROC cut-off value)
  ≤6.493 (5.6%)23 (92.0%)
  >6.4951 (94.4%)2 (8.0%)
Total54 (68.4%)25 (31.6%)