The Potential In Vitro Inhibitory Effects of Neurokinin-1 Receptor (NK-1R) Antagonist, Aprepitant, in Osteosarcoma Cell Migration and Metastasis

<div>Aprepitant inhibits the expression of MMP-2 and MMP-9 in the MG-63 osteosarcoma cell line. MG-63 cells were treated with aprepitant (AP) at the concentration of IC50 and 1/2 IC50 for 24 h, and subsequently, the mRNA expression levels of MMP-2 and MMP-9 were evaluated by qRT-PCR. 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BioMed Research International

fig3

Figure 3

Figure 3: The Potential In Vitro Inhibitory Effects of Neurokinin-1 Receptor (NK-1R) Antagonist, Aprepitant, in Osteosarcoma Cell Migration and Metastasis 

Figure 3 | The Potential In Vitro Inhibitory Effects of Neurokinin-1 Receptor (NK-1R) Antagonist, Aprepitant, in Osteosarcoma Cell Migration and Metastasis 