The Potential In Vitro Inhibitory Effects of Neurokinin-1 Receptor (NK-1R) Antagonist, Aprepitant, in Osteosarcoma Cell Migration and Metastasis

<div>Aprepitant reduces the protein expression of VEGF and NF-<i>κ</i>B. MG-63 cells were treated with aprepitant (AP) at the concentration of IC50 and 1/2 IC50 for 24 h, and subsequently, the protein expression levels of c VEGF and NF-<i>κ</i>B were assessed by western blotting. Western blot was conducted at least twice, and a representative picture is indicated. Western blot bands were quantitated by computer ImageJ software, plotted, and compared. 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BioMed Research International

fig6

Figure 6

Figure 6: The Potential In Vitro Inhibitory Effects of Neurokinin-1 Receptor (NK-1R) Antagonist, Aprepitant, in Osteosarcoma Cell Migration and Metastasis 

Figure 6 | The Potential In Vitro Inhibitory Effects of Neurokinin-1 Receptor (NK-1R) Antagonist, Aprepitant, in Osteosarcoma Cell Migration and Metastasis 