Research Article
Expression and Clinical Significance of CMTM6 and PD-L1 in Triple-Negative Breast Cancer
Table 3
Relationship between expression of CMTM6 and PD-L1 protein and clinicopathological features of TNBC.
| | Clinicopathological features | | Protein expression | | CMTM6 | PD-L1 | | — | + | PR (%) | value | — | + | PR (%) | value |
| | Age | | | | | | | | | | | ≤50 | 36 | 14 | 22 | 61.1 | 0.147 | 24 | 12 | 33.3 | 0.181 | | >50 | 53 | 25 | 28 | 52.8 | 39 | 14 | 26.4 | | Size | | | | | | | | | | | <3 | 50 | 25 | 25 | 50.0 | 0.043 | 38 | 12 | 24.0 | 0.022 | | ≥3 | 39 | 14 | 25 | 64.1 | 25 | 14 | 35.9 | | Lymph node metastasis | | | | | | | | | | | - | 54 | 27 | 28 | 51.9 | 0.028 | 47 | 8 | 14.8 | <0.001 | | + | 34 | 12 | 22 | 64.7 | 16 | 18 | 52.9 | | Distant metastasis | | | | | | | | | | | - | 81 | 36 | 45 | 55.6 | 0.298 | 60 | 21 | 25.9 | 0.273 | | + | 8 | 3 | 5 | 62.5 | 3 | 5 | 62.5 | | TNM stage | | | | | | | | | | | I | 73 | 34 | 39 | 53.4 | 0.003 | 57 | 16 | 21.9 | 0.039 | | II-III | 16 | 5 | 11 | 68.8 | 6 | 10 | 62.5 | | Histological grade | | | | | | | | | | | I | 38 | 15 | 23 | 60.5 | 0.187 | 31 | 7 | 18.4 | <0.001 | | II-III | 51 | 24 | 27 | 52.9 | 32 | 19 | 37.3 | | Vascular infiltration | | | | | | | | | | | - | 52 | 25 | 27 | 51.9 | 0.091 | 41 | 11 | 21.2 | 0.001 | | + | 37 | 14 | 23 | 62.2 | 22 | 15 | 40.5 | | Nerve invasion | | | | | | | | | | | - | 75 | 34 | 41 | 54.7 | 0.076 | 53 | 22 | 29.3 | 0.909 | | + | 14 | 5 | 9 | 64.3 | 10 | 4 | 28.6 | | TP53 | | | | | | | | | | | - | 23 | 11 | 12 | 52.2 | 0.531 | 17 | 6 | 26.1 | 0.429 | | + | 66 | 28 | 38 | 57.6 | 46 | 20 | 30.3 | | Ki67 | | | | | | | | | | | - | 10 | 8 | 2 | 20.0 | <0.001 | 10 | 0 | 0.0 | <0.001 | | + | 79 | 31 | 48 | 60.8 | 53 | 26 | 32.9 |
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PR: positive rate.
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