Kahweol Protects against Acetaminophen-Induced Hepatotoxicity in Mice through Inhibiting Oxidative Stress, Hepatocyte Death, and Inflammation

Figure 5

Effects of kahweol on production of inflammatory mediators and NF-κB activation in APAP-treated mice. (a) Hepatic levels of TNF-α and IL-6 proteins. (b) Hepatic mRNA levels of TNF-α, IL-6, MCP-1, and CXCL15. (c) Western blotting of p-NF-κB p65. (d) Quantification of western blot data for p-NF-κB p65. per group. , , and vs. control. ^# and ^### vs. APAP.

(a)

(b)

(c)

(d)