Research Article
SNORD15B and SNORA5C: Novel Diagnostic and Prognostic Biomarkers for Colorectal Cancer
Table 1
Correlations between SNORD15B expression and clinicopathological parameters.
| Characteristics | Case | SNORD15B expression# | | | Low | High |
| Sex | | | | 0.037 | 0.847 | Female | 206 | 102 | 104 | | | Male | 224 | 113 | 111 | | | Age (yr) | | | | 9.076 | 0.003 | ≤70 | 230 | 130 | 100 | | | >70 | 198 | 83 | 115 | | | TNM stage (AJCC) | | | | 0.228 | 0.633 | Stage I/II | 238 | 116 | 122 | | | Stage III/IV | 186 | 95 | 91 | | | Lymphatic invasion | | | | 3.901 | 0.048 | Negative | 236 | 129 | 107 | | | Positive | 151 | 67 | 84 | | | Venous invasion | | | | 0.056 | 0.813 | Negative | 278 | 141 | 137 | | | Positive | 94 | 49 | 45 | | | History of colon polyps | | | | 17.532 | < 0.001 | Negative | 239 | 132 | 107 | | | Positive | 122 | 39 | 83 | | |
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AJCC = American Joint Committee on Cancer. #Cutoff threshold of SNORD15B expression was median value in all patients in this cohort. . |