Research Article
SNORD15B and SNORA5C: Novel Diagnostic and Prognostic Biomarkers for Colorectal Cancer
Table 2
Correlations between SNORA5C expression and clinicopathological parameters.
| Characteristics | Case | SNORA5C expression# | | | Low | High |
| Sex | | | | 0.000 | 1.000 | Female | 206 | 103 | 103 | | | Male | 224 | 112 | 112 | | | Age (yr) | | | | 4.174 | 0.041 | ≤70 | 230 | 125 | 105 | | | >70 | 198 | 88 | 110 | | | TNM stage (AJCC) | | | | 0.486 | 0.486 | Stage I/II | 238 | 122 | 116 | | | Stage III/IV | 186 | 89 | 97 | | | Lymphatic invasion | | | | 12.681 | < 0.001 | Negative | 236 | 136 | 100 | | | Positive | 151 | 59 | 92 | | | Venous invasion | | | | 3.656 | 0.056 | Negative | 278 | 150 | 128 | | | Positive | 94 | 40 | 54 | | | History of colon polyps | | | | 9.443 | 0.002 | Negative | 239 | 127 | 112 | | | Positive | 122 | 44 | 78 | | |
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AJCC = American Joint Committee on Cancer. #Cutoff threshold of SNORA5C expression was median value in all patients in this cohort. . |