Predicting Hypertensive Disease in the First Trimester of Pregnancy: Risk Models and Analysis of Serum D-dimer Levels Combined with Plasma Pregnancy-Associated Protein A, Free β-Subunit of Human Chorionic Gonadotropin, and Fetal Nuchal Translucency
Table 2
DD, PAPP-A, free β-hCG, and NT concentration and MoM level in the different groups.
Groups
DD (ng/mL)
DD MoM
PAPP-A (mU/L)
PAPP-A MoM
Free β-hCG (ng/mL)
Free β-hCG MoM
NT (cm)
NT MoM
Control
150
226.60 (89.41-367.32)
0.84 (0.33-1.36)
4495 (1650-13545)
0.96 (0.36-2.75)
52.65 (16.87-156.23)
1.06 (0.40-2.88)
1.40 (0.73-2.34)
0.95 (0.52-1.53)
GH
126
269.52 (198.42-335.38)
1.00 (0.73-1.26)
3420 (837-10430)
0.96 (0.40-2.79)
42.4 (12.70-121.65)
0.97 (0.29-2.54)
1.40 (0.70-2.30)
0.96 (0.53-1.59)
PE
53
304.67 (193.88-361.89)
1.13 (0.72-1.34)
3720 (842-12120)
0.93 (0.30-2.20)
43.80 (10.61-315.00)
0.87 (0.29-6.93)
1.30 (0.56-2.71)
0.91 (0.40-1.69)
SPE
41
329.23 (256.03-397.95)
1.23 (0.95-1.64)
3320 (450-11495)
0.81 (0.14-2.74)
37.80 (15.10-168.05)
0.81 (0.35-2.63)
1.20 (0.70-1.95)
0.82 (0.52-1.19)
99.804
70.325
18.282
3.917
12.983
5.510
3.784
8.475
<0.001
<0.001
<0.001
0.271
0.05
0.138
0.286
0.037
GH: gestational hypertension; PE: preeclampsia; SPE: severe preeclampsia; DD: D-dimer; PAPP-A: pregnancy-associated plasma protein A; free β-hCG: free beta human chorionic gonadotropin; NT: nuchal translucency; MoM: multiple of median. ;.
