Research Article
Thyroid Hormone Levels Help to Predict Outcome of Critically Ill Patients Undergoing Early Neurological Rehabilitation
Table 4
Univariate (unadjusted) and multivariate (adjusted) logistic regression for predictive factors of favorable outcome (
).
| Independent variable | Unadjusted | Adjusted | OR | CI 95% | | OR | CI 95% | |
| Age | 0.96 | 0.95-0.98 | <.001 | 0.96 | 0.94-0.98 | <.001 | Male | 0.82 | 0.52-1.31 | .410 | | | | Time since injury | 0.98 | 0.96-0.99 | .043 | | | | Admission to ICU | 0.71 | 0.46-1.11 | .132 | | | | Etiology | | | | | | | Vascular | 0.96 | 0.63-1.49 | .867 | | | | Traumatic | 0.72 | 0.46-1.13 | .157 | | | | Anoxic | 3.26 | 1.24-8.56 | .017 | | | | BI | 1.13 | 1.06-1.17 | <.001 | | | | EFA | 1.10 | 1.08-1.13 | <.001 | 1.07 | 1.03-1.11 | <.001 | CRS-R | 1.15 | 1.11-1.18 | <.001 | | | | Complications | 0.63 | 0.53-0.76 | <.001 | | | | Hypophysis dysfunction | 0.54 | 0.18-1.64 | .276 | | | | fT3 | 1.59 | 1.09-2.32 | .016 | | | | fT4 | 1.28 | 0.57-2.86 | .554 | | | | TSH | 1.09 | 1.02-1.17 | .013 | 1.11 | 1.02-1.22 | .021 |
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aMann-Whitney test (low vs normal fT3); bChi2 test. BI = Barthel Index, CRS-R = Coma Recovery Scale-Revised, EFA = Early Functional Abilities, fT3 = free triiodothyronine, fT4 = free thyroxine, GOS = Glasgow Outcome Scale, TSH = thyroid-stimulating hormone. |