Resveratrol Induces Apoptosis, Suppresses Migration, and Invasion of Cervical Cancer Cells by Inhibiting the Hedgehog Signaling Pathway

Figure 4

PUR-inhibited downregulated the expression of SMO, Gli1, and Shh induced by RES in HeLa cells. Cells were treated with DMSO or RES or PUR or RES and PUR for 24 h; the expressions of Gli1, SMO, and Shh were analyzed by qPCR (a) and western blotting (b and c) in the HeLa cells. All date was from 3 independent experiments (, Tukey test). Control (Ctrl): HeLa cells were treated with DMSO; RES: HeLa cells were treated with RES; PUR: HeLa cells were treated with PUR; RES + PUR: HeLa cells were cotreated with RES and PUR.

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