VEGFA-Enriched Exosomes from Tendon-Derived Stem Cells Facilitate Tenocyte Differentiation, Migration, and Transition to a Fibroblastic Phenotype

Figure 2

TDSC-derived exosomes promote tenocyte differentiation, migration, and transition to a fibroblastic phenotype. (a) An MTT assay to investigate the proliferation of tenocytes in the control (normal culture medium) and TDSC-derived exosome-treated groups. (b) A transwell assay to monitor the migration of tenocytes in the control and TDSC-derived exosome-treated groups. (c) Quantification of the transwell assay data shown in (B). The mRNA (d) and protein (E-F) levels of collagen I, collagen III, α-SMA, Scx, and TnC in control and TDSC-derived exosome-treated tenocytes determined by RT-qPCR and western blotting. P <0.05 relative to the control group.

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