Research Article
Systematic Characterization of Expression Patterns and Immunocorrelations of Formin-Like Genes in Breast Cancer
Table 1
GO and KEGG pathway enrichment analyses of FMNL1 in BRCA.
| Term | Description | Size | NES | FDR |
| Biological process | | | | | GO:0045730 | Respiratory burst | 27 | 1.524 | 0.005 | GO:0071887 | Leukocyte apoptotic process | 103 | 1.488 | 0.005 | GO:0050867 | Positive regulation of cell activation | 298 | 1.490 | 0.005 | GO:0032633 | Interleukin-4 production | 34 | 1.504 | 0.005 | GO:0045576 | Mast cell activation | 58 | 1.502 | 0.005 | Cell component | | | | | GO:0042611 | MHC protein complex | 19 | 1.581 | <0.001 | GO:0001772 | Immunological synapse | 32 | 1.558 | <0.001 | GO:0071782 | Endoplasmic reticulum tubular network | 18 | -2.144 | <0.001 | GO:0042629 | Mast cell granule | 21 | 1.503 | 0.001 | GO:0098636 | Protein complex involved in cell adhesion | 35 | 1.517 | 0.001 | Molecular function | | | | | GO:0042287 | MHC protein binding | 24 | 1.563 | <0.001 | GO:0003823 | Antigen binding | 52 | 1.536 | <0.001 | GO:0016502 | Nucleotide receptor activity | 22 | 1.495 | 0.011 | GO:0004896 | Cytokine receptor activity | 88 | 1.476 | 0.012 | GO:0038187 | Pattern recognition receptor activity | 20 | 1.477 | 0.015 | KEGG | | | | | hsa05332 | Graft-versus-host disease | 37 | 1.616 | <0.001 | hsa05320 | Autoimmune thyroid disease | 50 | 1.608 | <0.001 | hsa05330 | Allograft rejection | 35 | 1.591 | <0.001 | hsa04940 | Type I diabetes mellitus | 41 | 1.588 | <0.001 | hsa05150 | Staphylococcus aureus infection | 52 | 1.584 | <0.001 |
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Note: NES: normalized enrichment score.
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