Systematic Characterization of Expression Patterns and Immunocorrelations of Formin-Like Genes in Breast Cancer

Table 2

GO and KEGG pathway enrichment analyses of FMNL2 in BRCA.

Term	Description	Size	NES	FDR
Biological process
GO:0002250	Adaptive immune response	368	2.101	<0.001
GO:0070661	Leukocyte proliferation	274	2.047	<0.001
GO:0050867	Positive regulation of cell activation	298	2.007	<0.001
GO:0007159	Leukocyte cell-cell adhesion	310	2.004	<0.001
GO:0002764	Immune response-regulating signaling pathway	452	2.004	<0.001
Cell component
GO:0044455	Mitochondrial membrane part	167	-2.188	<0.001
GO:0030964	NADH dehydrogenase complex	43	-2.292	<0.001
GO:0005743	Mitochondrial inner membrane	369	-2.305	<0.001
GO:0098798	Mitochondrial protein complex	213	-2.338	<0.001
GO:0070469	Respiratory chain	84	-2.387	<0.001
Molecular function
GO:0019955	Cytokine binding	119	1.987	<0.001
GO:0004896	Cytokine receptor activity	88	1.938	<0.001
GO:0003735	Structural constituent of ribosome	153	-2.251	<0.001
GO:0104005	Hijacked molecular function	70	1.834	0.001
GO:0015026	Coreceptor activity	39	1.810	0.002
KEGG
hsa04060	Cytokine-cytokine receptor interaction	281	2.016	<0.001
hsa05140	Leishmaniasis	71	1.961	<0.001
hsa04380	Osteoclast differentiation	126	1.944	<0.001
hsa04640	Hematopoietic cell lineage	93	1.916	<0.001
hsa05162	Measles	129	1.911	<0.001

Note: NES: normalized enrichment score.