Cleavage of AUF1 by Coxsackievirus B Affects DDX5 Regulatory on Viral Replication through iTRAQ Proteomics Analysis

Figure 4

The clusters in the network (). We numbered the clusters from 1 to 29 in descending order according to the MCODE score analyzed with the Cytoscape plugin. (a) Clusters that had more hub nodes were selected. (b) Clusters that had a higher proportion of all genes were selected. (c) Clusters were selected that had a larger value for the sum of parameter “degrees.” (d) Cluster 1, which contained the most hubs, was selected, and hubs are highlighted in yellow background. The red dashed box shows the hub nodes connected with AUF1 directly and mainly played roles in RNA regulation. Red lines indicate the interactions between the hubs.

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