Protective Effects of the Wenfei Buqi Tongluo Formula on the Inflammation in Idiopathic Pulmonary Fibrosis through Inhibiting the TLR4/MyD88/NF-κB Pathway

Table 2

The possible components of the WBT formula were predicted by network pharmacology.

Chinese medicines	Number	Components
Astragalus membranaceus (Fisch.) Bunge	20	Mairin, jaranol, hederagenin, quercetin, isorhamnetin, 3,9-di-O-methylnissolin, 5-hydroxyiso-muronulatol-2,5-di-O-glucoside, 7-O-methylisomucronulatol, 9,10-dimethoxyp-terocarpan-3-O-β-D-glucoside, bifendate, etc.
Scutellaria baicalensis Georgi	36	Diop, panicolin, skullcapflavone II, baicalein, supraene, carthamidin, norwogonin, salvigenin, ent-epicatechin, sitosterol, etc.
Salvia miltiorrhiza Bunge	65	Salvilenone, salviolone, sugiol, luteolin, miltipolone, miltirone, baicalin, manool, digallate, sugiol, etc.
Polygonum cuspidatum Siebold & Zucc	10	6,8-Dihydroxy-7-methoxyxanthoneluteolin, beta-sitosterol, physciondiglucoside, torachrysone-8-O-beta-D-(6-oxayl)-glucoside, quercetin, rhein, (+)-catechin, picralinal, physovenine, etc.
Angelica sinensis (Oliv.) Diels	2	Stigmasterol, beta-sitosterol
Ligusticum striatum DC.	7	Mandenol, myricanone, perlolyrine, senkyunone, wallichilide, sitosterol, FA
Prunus persica (L.) Batsch	23	Hederagenin, beta-sitosterol, campesterol, 3-O-p-coumaroylquinic acid, sitosterol alpha1, gibberellin 7, gibberellin 17, 2,3-didehydro GA70, gibberellin A44, populoside_qt, etc.
Pheretima aspergillum (E. Perrier)	10	4-Guanidino-1-butanol, cholesterol, cholesteryl ferulate, guanidine, guanine(1,7-dihydro-form), guanosine, hypoxanthine, hyrcanoside, xanthine, xanthinin, etc.
Aster tataricus L.f.	19	Rabdosinatol, shionone, galangin, isorhamnetin, beta-sitosterol, epifriedelanol acetate, kaempferol, spinasterol, luteolin, quercetin, etc.
Tussilago farfara L.	22	Tussilagolactone, beta-sitosterol, taraxanthin, kaempferol, quercetin, senkirkine, tussilagin, femara, methyl 3-o-caffeoylquinate, alpha-Carotene-5,6-epoxide, etc.
Pinellia ternata (Thunb.) Makino	13	Cavidine, gondoic acid, coniferin, baicalein, beta-sitosterol, cycloartenol, baicalin, stigmasterol, 24-ethylcholest-4-en-3-one, 10,13-eicosadienoic, etc.
Clematis chinensis Osbeck	7	(4aS,6aR,6aS,6bR,8aR,10R,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12aheptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid, (6Z,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, beta-sitosterol, stigmasterol, clematosideA’_qt, embinin, heptyl phthalate
Siegesbeckia orientalis L.	9	Stigmasterol, hederagenin, beta-sitosterol, 15alpha-Hydroxy-ent-kaur-16-en-19-oic acid, vernolic acid, coronaridine, siegesesteric acid II, siegesmethyletheric acid, (1R)-1-[(2S,4aR,4bS,7R,8aS)-7-hydroxy-2,4b,8,8-tetramethyl-4,4a,5,6,7,8a,9,10-octahydro-3H-phenanthren-2-yl]ethane-1,2-diol