Neuroprotective Effect of Polyherbal Recipe Containing Ginger, Chinese Date, and Wood Ear Mushroom against Ischemic Stroke with Metabolic Syndrome Condition via Epigenetic Modification of Inflammation and Oxidative Stress

Table 1

Effect of the polyherbal recipe containing ginger, Chinese date, and wood ear mushroom (GCJ) at the doses of 100, 200, and 300 mg/kg BW on oxidative stress parameters including malondialdehyde (MDA) level and the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in the cerebral cortex (/group).

Treatment group	MDA level (ng/mg protein)	SOD activity (units/mg·protein)	CAT activity (units/mg·protein)	GPx activity (unit/mg·protein)
ND + vehicle
HCHF+sham+vehicle
HCHF+MCAO+vehicle	^aa,bb	^aaa,bbb	^aaa,bbb	^aa
HCHF+MCAO+vitamin C
HCHF+MCAO+piracetam
HCHF+MCAO+GCJ100
HCHF+MCAO+GCJ200
HCHF+MCAO+GCJ300

Data were presented as . ^aa,aaa value < 0.01 and 0.001, respectively, compared to ND+vehicle; ^bb,bbb value < 0.01 and 0.001, respectively, compared to HCHF+sham+vehicle; value < 0.05, 0.01, and 0.001, respectively, compared to HCHF+MCAO+vehicle.