D-Dimer-to-Albumin Ratio: A Novel Indicator to Predict Poor Outcomes in Patients with HBV-Associated Decompensated Cirrhosis
Table 1
Comparisons of baseline characteristics between the survivors and the nonsurvivors.
All patients ()
Non-survivors ()
Survivors ()
Gender (female/male)
30/142
9/25
21/117
0.195
Age (years)
50.0 (43.0-58.5)
49.5 (40.0-57.0)
50.0 (44.0-59.0)
0.890
Total protein (g/dL)
5.86 (5.37-6.29)
5.72 (5.27-6.30)
5.89 (5.43-6.29)
0.284
Albumin (g/dL)
3.00 (2.75-3.37)
2.89 (2.62-3.19)
3.02 (2.77-3.41)
0.042
ALT (U/L)
67.0 (29.5-204.0)
71.0 (38.0-237.0)
64.5 (29.0-182.0)
0.312
AST (U/L)
73.0 (41.0-151.5)
75.0 (48.0-182.0)
73.0 (40.0-129.0)
0.250
Serum creatinine (μmol/L)
66.0 (57.5-79.0)
74.5 (58.0-120.0)
65.5 (57.0-75.0)
0.025
Total bilirubin (μmol/L)
171.4 (40.5-340.4)
278.9 (131.0-422.6)
146.5 (35.0-332.9)
0.003
INR
1.52 (1.29-1.85)
1.96 (1.52-2.42)
1.47 (1.26-1.76)
<0.001
Platelet (×109/L)
83.5 (54.5-118.0)
77.5 (63.0-130.0)
84.0 (53.0-115.0)
0.722
D-dimer (mg/L)
2.14 (0.89-3.79)
3.82 (2.18-6.18)
1.86 (0.82-3.01)
<0.001
DAR
0.73 (0.28-1.20)
1.33 (0.76-2.35)
0.66 (0.24-1.04)
<0.001
MELD score
16.8 (11.2-21.2)
21.7 (18.5-25.7)
14.8 (10.1-20.2)
<0.001
Data are expressed as number or median (interquartile range). Abbreviations: ALT: alanine aminotransferase; AST: aspartate aminotransferase; INR: international normalized ratio; DAR: D-dimer-to-albumin ratio; MELD: Model for End-Stage Liver Disease.
