Research Article

Assessment of the Concentration of Endogenous Factors Regulating Angiogenesis, VASH-1 and VEGF-A, in the Blood Serum of Patients with Neuroendocrine Neoplasms

Table 1

Characteristics of the study and the control group with the values of the Kruskal-Wallis test.

Study groupControl group value

Number of patients, (%)120 (100%)69 (100%)
Age (years), 0.001
BMI (kg/m2), 0.245
Gender, (%)Female69 (57.5%)45 (65.2%)0.493
Male51 (42.5%)24 (34.8%)
Smoking, (%)Yes14 (11.7%)19 (27.5%)0.065
No106 (88.3%)50 (72.5%)
Localization of the primary tumor for GEP-NET cases, (%)Pancreas10 (8.3%)
Duodenum40 (33.3%)
Small intestine5 (4.2%)
Rectum21 (17.5%)
Appendix14 (11.7%)
Stomach4 (3.3%)
Unknown6 (5.0%)
Localization of the primary tumor for BP-NET cases, (%)Lung20 (16.7%)
Histological grade for GEP-NET cases, (%)NET G167 (55.8%)
NET G229 (24.2%)
NET G34 (3.3%)
Histological type for BP-NET cases, (%)Typical carcinoid (TC)14 (11.7%)
Atypical carcinoid (AC)5 (4.2%)
Large cell neuroendocrine carcinoma (LC-NEC)1 (0.8%)
Metastasis, (%)Total53 (44.2%)
Lymph nodes42 (35.0%)
Liver34 (28.3%)
Bones7 (5.8%)
Clinical stage, (%)Stage I46 (38.33%)
Stage II17 (18.33%)
Stage III22 (18.33%)
Stage IV35 (29.17%)