Research Article
SOX8 Knockdown Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer by Inhibiting the Notch Signaling Pathway
Figure 2
Expression of SOX8 and Notch signaling detected in Enza-R cells. (a) Both LNCaP and Enza-R cells were treated with increasing concentrations of enzalutamide for 24 hours, and the IC50 was detected by a Cell Counting Kit-8 (CCK-8) assay. (b–d) mRNA and protein expression of SOX8, Notch4, and Hes5 assessed by RT-PCR, Western blot, and immunofluorescence (×200). and . ns: no significance.
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