Carbon Monoxide-Releasing Molecule-3 Suppresses the Malignant Biological Behavior of Tongue Squamous Cell Carcinoma via Regulating Keap1/Nrf2/HO-1 Signaling Pathway

Figure 1

The effect of CORM-3 on TSCC cell proliferation. (a) CAL27 or SCC4 cells were incubated with 0, 100, 200, 400, and 800 μM CORM-3, respectively, for 24 h. Cell proliferation was assessed by a CCK-8 kit. (b, c) CORM-3 of 0, 200, 400, and 800 μM was applied to CAL27 and SCC4 cells, respectively. Cell proliferation was measured at 6, 12, 24, 48, and 72 h after treatment with CCK-8. (d) CAL27 or SCC4 cells were incubated with 400 μM CORM-3 and iCORM-3 for 24 h. and vs. the control group, respectively.

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