[Retracted] Might Patients with Metastatic Gastrointestinal Stromal Tumors Benefit from Operative Management? A Population-Based Retrospective Study
Table 3
Multivariable analysis of the risk of GSS and OS in metastatic GIST patientsa.
Variable
GSS
OS
Adjusted HR, 95% CI
value
Adjusted HR, 95% CI
value
Surgery
Yes
1 [reference]
NA
1 [reference]
NA
No
2.42 (2.00-2.93)
<0.001
2.27 (1.90-2.71)
<0.001
Chemotherapy
Yes
1 [reference]
NA
1 [reference]
NA
No/unknown
1.39 (1.16-1.68)
<0.001
1.47 (1.24-1.74)
<0.001
Age at diagnosis, y
1..02 (1.02-1.03)
<0.001
1.03 (1.02-1.04)
<0.001
Gender
Male
1 [reference]
NA
1 [reference]
NA
Female
0.90 (0.76-1.07)
0.240
0.87 (0.74-1.02)
0.084
Race
White
1 [reference]
NA
1 [reference]
NA
Black
0.99 (0.79-1.24)
0.920
1.03 (0.84-1.27)
0.785
Other
0.77 (0.59-1.02)
0.072
0.87 (0.67-1.12)
0.266
Marital status
Married
1 [reference]
NA
1 [reference]
NA
Unmarried
1.17 (0.98-1.39)
0.086
1.25 (1.06-1.48)
0.007
Tumor site
Stomach
1 [reference]
NA
1 [reference]
NA
Small intestine
0.93 (0.76-1.15)
0.516
0.92 (0.76-1.12)
0.411
Other digestive organs
1.04 (0.81-1.33)
0.777
1.01 (0.79-1.28)
0.959
Non-digestive organs
1.36 (1.00-1.84)
0.049
1.46 (1.11-1.93)
0.007
Tumor size, cm
<2
0.81 (0.51-1.28)
0.365
0.86 (0.55-1.32)
0.482
2-4.9
0.66 (0.49-0.87)
0.004
0.69 (0.53-0,.90)
0.006
5-9.9
0.79 (0.65-0.96)
0.016
0.84 (0.80-1.00)
0.054
≥10
1 [reference]
NA
1 [reference]
NA
Grade
Poor differentiated or undifferentiated
1 [reference]
NA
1 [reference]
NA
Well or moderately differentiated
0.59 (0.41-0.85)
0.004
0.57 (0.40-0.80)
0.001
Abbreviations: NA: not applicable; HR: hazard ratio. aAge at diagnosis and year at diagnosis were included as continuous variables; all other covariates were categorical.
