Baicalin Attenuated Aβ_1-42-Induced Apoptosis in SH-SY5Y Cells by Inhibiting the Ras-ERK Signaling Pathway

Figure 5

Inhibition of Ras-ERK signaling pathway activation in Aβ_1-42-treated SH-SY5Y cells by baicalin. (a) SH-SY5Y cell extracts were prepared and analyzed by Western blotting using Ras, P-ERK, total ERK, and cyclin D1 antibodies. β-Actin antibodies were used as a reference. (b) Ras protein expression normalized to β-actin. (c) p-ERK levels normalized to total ERK expression. (d) Cyclin D1 expression normalized to β-actin. The protein expression is presented as the . , represents , and represents .

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