Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy

Figure 9

The correlation analysis between core genes renal tubulointerstium and clinical features in DN patients. (a) The significantly negative correlation between core genes in renal tubulointerstium and GFR in DN patients; (b) the significantly positive correlation between core genes in renal tubulointerstium and proteinuria in DN patients; (c) the significantly positive correlation between core genes in renal tubulointerstium and SCR in DN patients; (d) the significantly positive correlation between core genes in renal tubulointerstium and ACR in DN patients; DN: diabetic nephropathy; GFR: glomerular filtration rate; MDRD: modification of diet in renal disease; CG: Cockcroft Gault; SCR: serum creatinine level; ACR: urine albumin creatinine ratio; Pearson correlation of log2 transformed mRNA levels of core genes and clinical features in DN patients, was statistically significant.

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