LINC02273 Promotes Hepatocellular Carcinoma Progression via Retaining β-Catenin in the Nucleus to Augment Wnt Signaling

Figure 6

The schematic model of this study. LINC02273 is mainly localized in the nucleus, where it binds to β-catenin to increase its stabilization and augments downstream signaling of Wnt/β-catenin axis. Accordingly, interference of LINC02273 expression is a potential strategy to decrease Wnt/β-catenin signaling and thus suppress HCC progression.