Luteolin Isolated from <i>Polygonum cuspidatum</i> Is a Potential Compound against Nasopharyngeal Carcinoma

<div>Luteolin induces changes in the expression of related proteins in human NPC CNE2 cells. (a‑c) Western blot results showed when compared to the control group, the expression of p-ERK1/2, ERK1/2, AKT, and PI3K, the related proteins in the PI3K-AKT signaling pathway diagram, and the expression of the proliferation and apoptosis-related proteins PCNA and XIAP expression levels all decreased to varying degrees after luteolin treatment for 36 h (<span class="nowrap"><svg height="12.7112pt" id="M63" style="vertical-align:-3.403299pt" version="1.1" viewbox="-0.0498162 -9.3079 186.829 12.7112" width="186.829pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M433 39L423 65C413 59 399 54 387 54C370 54 352 69 352 114V299C352 352 342 392 307 422C285 440 255 449 225 449C168 437 102 399 75 379C56 365 44 353 44 339C44 315 69 296 87 296C101 296 111 303 116 319C124 349 133 371 145 385C156 397 171 404 190 404C241 404 275 364 275 291V274C253 256 180 229 120 209C65 190 39 159 39 110C39 47 88 -12 159 -12C189 -12 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BioMed Research International

fig14

Figure 14

Figure 14: Luteolin Isolated from <i>Polygonum cuspidatum</i> Is a Potential Compound against Nasopharyngeal Carcinoma 

BioMed Research International

Luteolin Isolated from Polygonum cuspidatum Is a Potential Compound against Nasopharyngeal Carcinoma

Figure 14