[Retracted] Depletion of Fibroblast Growth Factor 12 Restrains the Viability, Stemness, and Motility of Colorectal Cancer

Figure 5

FGF12 knockdown inhibits the CRC tumor growth in vivo. (a) In xenograft tumor models, FGF12 knockdown obviously slowed down growth of tumor (). (b) FGF12 knockdown did not affect the body weight of nude mice. (c) FGF12 knockdown obviously inhibited tumor weight of nude mice. (d) Immunohistochemistry staining of Ki-67, FGF12, cleaved-caspase 3, E-cadherin, N-cadherin, vimentin, NANOG, and OCT4 in xenograft tissues. (e) The expression of p-PI3K, PI3K, p-AKT (473 S), p-AKT (T308), and AKT in xenograft tissues were analyzed by WB. CRC: colorectal cancer; , .

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