Research Article
A Novel-Defined Necroptosis-Related miRNA Signature for Forecasting the Prognosis of Low-Grade Glioma
Table 3
Modified Fisher test of hsa-miR-200a-5p and clinical parameters.
| | Characteristic | Low expression of hsa-miR-200a-5p | High expression of hsa-miR-200a-5p | |
| | 264 | 265 | | | WHO grade, (%) | | | 0.393 | | G2 | 113 (24.2%) | 108 (23.1%) | | | G3 | 115 (24.6%) | 131 (28.1%) | | | IDH status, (%) | | | <0.001 | | WT | 11 (2.1%) | 86 (16.3%) | | | Mut | 251 (47.7%) | 178 (33.8%) | | | 1p/19q codeletion, (%) | | | <0.001 | | Codel | 113 (21.4%) | 59 (11.2%) | | | Noncodel | 151 (28.5%) | 206 (38.9%) | | | Primary therapy outcome, (%) | | | 0.077 | | PD | 45 (9.8%) | 65 (14.2%) | | | SD | 76 (16.6%) | 72 (15.7%) | | | PR | 38 (8.3%) | 25 (5.4%) | | | CR | 73 (15.9%) | 65 (14.2%) | | | Gender, (%) | | | 0.405 | | Female | 115 (21.7%) | 126 (23.8%) | | | Male | 149 (28.2%) | 139 (26.3%) | | | Race, (%) | | | 0.653 | | Asian | 4 (0.8%) | 4 (0.8%) | | | Black or African American | 9 (1.7%) | 13 (2.5%) | | | White | 246 (47.5%) | 242 (46.7%) | | | Age, (%) | | | 0.004 | | ≤40 | 149 (28.2%) | 115 (21.7%) | | | >40 | 115 (21.7%) | 150 (28.4%) | | | Histological type, (%) | | | 0.002 | | Astrocytoma | 83 (15.7%) | 113 (21.4%) | | | Oligoastrocytoma | 62 (11.7%) | 71 (13.4%) | | | Oligodendroglioma | 119 (22.5%) | 81 (15.3%) | | | Laterality, (%) | | | 0.320 | | Left | 134 (25.6%) | 123 (23.5%) | | | Midline | 2 (0.4%) | 5 (1%) | | | Right | 124 (23.7%) | 136 (26%) | | | OS event, (%) | | | 0.003 | | Alive | 212 (40.1%) | 182 (34.4%) | | | Dead | 52 (9.8%) | 83 (15.7%) | | | DSS event, (%) | | | 0.004 | | Alive | 215 (41.3%) | 184 (35.3%) | | | Dead | 47 (9%) | 75 (14.4%) | | | PFI event, (%) | | | 0.023 | | Alive | 173 (32.7%) | 147 (27.8%) | | | Dead | 91 (17.2%) | 118 (22.3%) | |
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