Chalcone Derivatives as Potential Inhibitors of P-Glycoprotein and NorA: An In Silico and In Vitro Study

Figure 2

Two-dimensional interaction schemes inside the two NorA ligand-binding sites: the central channel (a) and the Walker B motif (b) of the four selected chalcones F29, F88, F90, and F91.

(a) The central channel

(b) The Walker B motif