Chalcone Derivatives as Potential Inhibitors of P-Glycoprotein and NorA: An In Silico and In Vitro Study

Table 1

Predicted IC₅₀ values (μM) on NorA and docking scores (kJ mol^-1) of the four selected in-house chalcones inside the binding sites.

Chalcone	Predicted IC50	Docking score (kJ mol^-1)
		Central channel	Walker B motif
F29	88.27	-23.67	-26.69
F88	3.84	-22.65	-29.06
F90	5.24	-23.76	-30.33
F91	5.07	-24.96	-27.78