Identification of RALA as a Therapeutic Target and Prognostic Predictor of Osteosarcoma

Figure 3

Immune infiltration analysis and DNA methylation analysis of RALA in OS. (a, b) Enrichment scores (a) of RALA in different immune cells in sarcoma. The positive correlation and significance were given in the heat map (b). ; . (c) Correlation between RALA and immune cells was presented using TIMER tool. (d, e) Single-cell sequencing results show differential expression of RALA in immune cells and stromal cells (d). Expression levels of RALA in different immune cells were given in (e). . (f) Correlation between RALA expression and DNA methylation level was detected in different sites of RALA TSS in OS. (g–j) Correlation between m6A-related genes and RALA in OS tissues from TARGET was presented using coexpression heat map, containing writers (g), reader (h), and erasers (i). Positive correlation and significance were given in the heat map (j). ; ; .

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