Research Article

Nimotuzumab Concurrent with Gemcitabine as First-Line Treatment of Locally Advanced or Metastatic Pancreatic Adenocarcinoma

Table 2

General information on adverse events.

Categories by patient1 and adverse events (AEs)Locally advanced (%)Metastatic (%)Recurrent (%)Total (%)

Patients with an adverse event18 (78.3)27 (67.5)4 (100)49 (73.1)
Patients with TRAE1 (4.35)2 (5.0)1 (25)4 (5.9)
Patients with grade 3-4 TRAE1 (2.5)1 (1.5)
Adverse events125 (39.2)160 (50.2)34 (10.7)319 (100)
Treatment-related AE11 (8.8)14 (8.7)1 (2.9)26 (8.1)
Grade 3-4 treatment-related AE4 (2.5)4 (1.2)

1Subject can be included in more than one category. TRAE: treatment-related adverse events.