Neurological Effects of Combining Low Toxic Dose of Tramadol and Nicotine: An Animal Model Evidence of Endoplasmic Reticulum Stress

Figure 1

Sections of the brain cortex of six groups showing increased aggregates of inflammatory cells in the cortex of G1 (high-dose tramadol) and G3 (nicotine+tramadol) (yellow arrows) (×400,400,100,400,400,400, respectively).