Neurological Effects of Combining Low Toxic Dose of Tramadol and Nicotine: An Animal Model Evidence of Endoplasmic Reticulum Stress

Figure 6

Immunohistochemical staining sections of brain white matter of six groups showing different expressions of CHOP antibody in comparison to negative G6 (normal control). Caspase-8 antibody is negative in all groups except mild expression in G4 (nicotine). P53 antibody is negative in all groups (×400 all).