Molecular Investigation of the Antitumor Effects of Monoamine Oxidase Inhibitors in Breast Cancer Cells

Figure 4

The effect of MAO-AIs on (a) MAO-A, BCL-2, and VEGF genes and (b) MAO-A activity expression in MDA-MB-231 and T-47D breast cancer cell lines. Fold difference was expressed as and was measured using ΔΔCt method; value < 0.05 expresses significantly different from respective untreated cells status; ^ns (not significant); ; ; ; (according to GraphPad Prism 9). MAO-A: monoamine oxidase A; Bcl-2: the gene for B-cell lymphoma 2; VEGF: the gene for vascular endothelial growth factor; GAPDH: the gene for glyceraldehyde 3-phosphate dehydrogenase.

(a)

(b)