Chronic Gastric Ulcer Healing Actions of the Aqueous Extracts of Staple Plant Foods of the North-West, Adamawa, and West Regions of Cameroon

Table 5

Effect of aqueous extracts on some parameters of oxidative stress and NO level in gastric tissue “unhealed ulcer” model.

Treatments	Dose (mg/kg)	MDA (μmol/g tissue)	GSH (μmol/g tissue)	Catalase (mM H2O2/min/g tissue)	SOD (units/g tissue)	Nitrites (μmol/g tissue)
Normal	—
Control 1	—		^+++		^+++
Control 2	—		^abc,++	^abc,+++
Control 3 (sucralfate)	50		^,+++	^abc,^,+++	^abc,^,+++	^a
C. olitorius	200	^a,	^,+++	^a,	^+++	^ab
C. olitorius	400		^++	^abc,+++	^,+++
Solanum nigrum	200		^ab,^,+++		^+++
S. nigrum	400		^+++	^abc,^,++	^,+++
Vigna unguiculata	200		^ab,^,+++		^abc,^,+++
Vigna unguiculata	400				^,+++
T. pentandra	200		^a,^,+++		^+++
T. pentandra	400		^,+++		^,+++
“nkui” spices	200	^abc,^,+++	^abc,^,+++	^ab,^,++	^+++	^a
“nkui” spices	400	^abc,^,+++	^,+++	^a,^,++	^,+++
“Yellow soup” spices	200		^abc,^,+++	^ab,	^+++
“Yellow soup” spices	400	^ab,^,+			^+++

Normal: group that did not undergo ulcer induction; control 1: rats sacrificed on the 4th day after ulcer induction; control 2: ulcerated rats treated with distilled water for 14 days; control 3: group of rats received sucralfate at a dose of 50 mg/kg. The values in the table represent the ; ^a, ^ab, and ^abc: statistically significant difference from control 1; , , and : statistically significant difference from control 2; ⁺, ⁺⁺, and ⁺⁺⁺: statistically significant difference from normal.