Research Article

Chronic Gastric Ulcer Healing Actions of the Aqueous Extracts of Staple Plant Foods of the North-West, Adamawa, and West Regions of Cameroon

Table 6

Effects of aqueous extracts on oxidative stress parameters in gastric tissue ethanol/stress model.

TreatmentDose (mg/kg)MDA (μmol/g tissue)GSH (μmol/g tissue)Catalase (mM H2O2/min/g tissue)SOD (unit/g tissue)Nitrites (μmol/g tissue)

Normal
Control 1++++++
Control 2+
Control3ab,+++a,++
Control 450,ab,+++++
Corchorus olitorius200++ab,++++
Corchorus olitorius400abc,+++a,++
Solanum nigrum200aa
Solanum nigrum400abc,++a,+ab,,+
Vigna unguiculata200abc,,++a,+a,,+,++
Vigna unguiculata400abc,+++ab,+
T. pentandra200ab,+++a,++++abc,,++
T. pentandra400+abc,ab,,+++
“Nkui” spices200abc,,+++a
“Nkui” spices40035.68 ± 1.70abc,,+69.61 ± 3.06ab,,+++189.2 ± 9.16ab,,+1.13 ± 0.032.47 ± 0.70,+++
“Yellow soup” spices20023.31 ± 4.03105.9 ± 2.44a,+167.1 ± 4.62+1.05 ± 0.321.14 ± 0.11,++
“Yellow soup” spices40011.71 ± 0.70abc,+109.9 ± 3.11a,+189.6 ± 2.85ab,,+3.27 ± 0.310.98 ± 0.17++

Normal: group that did not undergo ulcer induction; control 1: rats sacrificed on the 4th day after ulcer induction; control 2: rats sacrificed on the 4th day after ulcer induction; control 3: ulcerated rats treated with distilled water for 10 days; control 4: group of rats treated with sucralfate at a dose of 50 mg/kg. The values in the table represent the ; a, ab, and abc: statistically significant difference from control 2; , , and : statistically significant difference from control 3; +, ++, and +++: statistically significant difference from normal.