A Novel Cuproptosis-Associated Gene Signature to Predict Prognosis in Patients with Pancreatic Cancer

Figure 2

Construction process of Cox risk model: (a) differential analysis results of 178 tumor tissues and 171 normal tissues in TCGA-GTEx database; (b) the expression levels of Cox risk model genes in tumor tissues and normal tissues; (c) the upset plot shows the number and cross-linking of coexpressed genes of the 19 cuproptosis genes; (d) distribution of Lasso coefficients of the 202 potential prognostic cuproptosis-related genes in the training group; (e) the cross-validation curve of Lasso regression shows the best penalty parameter value in the training group; (f) the 8 prognostic cuproptosis-related gene signature constructs the Cox risk model in the training group; (g) the correlation between 8-gene signature and 19 cuproptosis genes. FC: fold change. .

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