Role of Kir4.1 Channels in Aminoglycoside-Induced Ototoxicity of Hair Cells

Figure 1

Screening of hair cell markers in HEI-OC1 cells and the expressions of the main potassium channels. HEI-OC1 cells were cultured at 33°C followed by 39°C, each for 5 days. Expression of marker genes in hair cells was confirmed and expression of main potassium channels was confirmed. (a) RT-PCR results of hair cell markers in HEI-OC1 cells. RT-PCR was performed on day 5 of incubation at 33°C and 39°C. Kidney tissue was used as a control. (b) Expression of marker genes and main potassium channels were confirmed in day 5 HEI-OC1 cells at 33°C and 39°C.

(a)

(b)