Role of Kir4.1 Channels in Aminoglycoside-Induced Ototoxicity of Hair Cells

Figure 5

Changes in HEI-OC1 cells upon Kir4.1 channel inhibition. (a) qRT-PCR results of HEI-OC1 cells cultured 39°C for 3 days following Kir4.1 inhibition. (b) Expression of Kir4.1 with ototoxic drug treatment in HEI-OC1 cells cultured at 39°C for 3 days following siRNA transfection. (c) CCK assay of cell viability following transfection with Kir4.1 siRNA. (d) CCK assay results of Kir4.1 channel inhibition HEI-OC1 cells after 72 h of treatment with ototoxic drugs.

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