MiR-100 rs1834306 A>G Increases Biliary Atresia Risk in Southern Han Chinese Children

Table 1

Association between the miR-100 rs1834306 A>G polymorphism and biliary atresia susceptibility.

Genotype	Cases; ()	Controls; ()	^a	Crude OR; (95% CI)		Adjusted OR; (95% CI)^b	^b
rs1834306 A>G ()
AA	150 (30.99)	480 (33.22)		1.00		1.00
AG	241 (49.79)	730 (50.52)		1.06 (0.84-1.34)	0.646	1.05 (0.81-1.37)	0.699
GG	93 (19.21)	235 (16.26)		1.27 (0.94-1.71)	0.126	1.44 (1.02-2.03)	0.041
Additive			0.151	1.12 (0.96-1.30)	0.152	1.17 (0.99-1.39)	0.065
Dominant	334 (69.01)	965 (66.78)	0.366	1.11 (0.89-1.38)	0.366	1.14 (0.89-1.46)	0.307
Recessive	391 (80.79)	1210 (83.74)	0.135	1.23 (0.94-1.60)	0.135	1.39 (1.02-1.89)	0.036

Notes: the results are in bold, if the 95% CI excluded 1 or the values less than 0.05. ^a test for genotype distributions between biliary atresia patients and control. ^bAdjusted for age and gender. Abbreviations: OR: odds ratio; CI: confidence interval; HWE:Hardy-Weinberg equilibrium.