Efficiency of Hesperidin against Liver Fibrosis Induced by Bile Duct Ligation in Rats

Table 2

Group comparisons respecting liver enzymes and serum bilirubin.

Group	Parameter
	AST (IU/L)	ALT (IU/L)	ALP (IU/L)	LDH (IU/L)	Total bilirubin (mg/dL)	Direct bilirubin (mg/dL)
Healthy	^^	^^	^^	^^	^^	^^
Sham	^^	^^	^^	^^	^^	^^
BDL	^#	^#^	^#^	^#	^#	^#
BDL+VitC (4.25 μg/kg)	^#	^#	^#	^#	^#	^#
BDL+Hesp (100 mg/kg)	^#	^#^^	^#	^#	^#^^	^#^^
BDL+Hesp (200 mg/kg)	^^	^#^^	^^	^#^^	^#^^	^#^^

Data are presented as (). BDL: bile duct ligation; VitC: vitamin C; Hesp: hesperidin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; LDH: lactate dehydrogenase; ALP: alkaline phosphatase. ^#Significant difference with the sham group. Significant difference with the BDL+Vehicle group. ^{^}Significant difference with the BDL+VitC group.