Research Article
Insampaedok-San Extract Exerts an Immune-Enhancing Effect through NF-κB p65 Pathway Activation
Table 3
Key targets of ISE based on the results of PPI network topological analysis.
| No. | UniProt ID | Gene | Degree | Relevance score |
| 1 | P27361 | MAPK3 | 8 | 9.86 | 2 | P40763 | STAT3 | 8 | 9.45 | 3 | Q16539 | MAPK14 | 8 | 9.49 | 4 | P42224 | STAT1 | 8 | 10.01 | 5 | P01584 | IL1B | 7 | 19.65 | 6 | P05231 | IL6 | 7 | 21.34 | 7 | P01375 | TNF | 7 | 29.00 | 8 | P60568 | IL2 | 7 | 13.50 | 9 | P12931 | SRC | 4 | 10.84 |
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