Evaluation of Systemic Genotoxic/Oxidative and Proinflammatory Effects in Workers of a Titanium Dioxide Production Plant

Table 9

hOGG1, XRCC1, and GST genotype distribution in exposed workers and controls.

	All subjects		Workers producing TiO2		Office workers		External controls		value
		%		%		%		%
hOGG1
mut+het	15	34.9	7	31.8	1	33.3	7	38.9	Fisher’s exact
wt	28	65.1	15	68.2	2	66.7	11	61.1
XRCC1
mut+het	36	57.1	20	50.0	4	80,0	12	66.7	Chi-square test () 0.334
wt	27	42.9	20	50.0	1	20.0	6	33.3
GSTT1
pos	54	85.7	34	85.0	4	80.0	16	88.9	Fisher’s exact
null	9	14.3	6	15	1	20.0	2	11.1
GSTM1
pos	26	41.3	11	27.5	2	40.0	13	72.2	Fisher’s exact
null	37	58.7	39	72.5	3	60.0	5	27.8

indicates statistically significant.