Research Article
Nomogram to Predict Long-Term Overall Survival and Cancer-Specific Survival of Radiotherapy Patients with Nasopharyngeal Carcinoma
Table 1
Baseline characteristics of patients with nasopharyngeal carcinoma in the training cohort and validation cohort (
, %).
| | Characteristics | Total (cases, %) | Modeling group (cases, %) | Validation group (cases, %) | value |
| | Total | 5663 | 3967 | 1696 | | | Age group (years) | | | | | | <50 | 1941 (34.28) | 1362 (34.33) | 579 (34.14) | 0.92 | | 50-64 | 2335 (41.23) | 1637 (41.27) | 698 (41.15) | | ≥65 | 1387 (24.49) | 968 (24.40) | 419 (24.71) | | Sex | | | | | | Male | 4008 (70.78) | 2823 (71.16) | 1185 (69.87) | 0.619 | | Female | 1655 (29.22) | 1144 (11.87) | 511 (30.13) | | Race | | | | | | Black | 685 (12.10) | 471 (11.87) | 214 (12.62) | 0.980 | | White | 2665 (47.06) | 1873 (47.21) | 792 (46.69) | | Asian/Pacific islander | 2233 (39.43) | 1564 (39.43) | 669 (39.45) | | Indian/Alaska native | 80 (1.41) | 59 (1.49) | 21 (1.24) | | Marital status | | | | | | Single | 1242 (21.93) | 888 (22.38) | 354 (20.87) | 0.893 | | Married | 3540 (62.51) | 2473 (62.34) | 1067(62.91) | | Divorced | 521 (9.20) | 362 (9.13) | 159 (9.38) | | Windowed/separated | 360 (6.36) | 244 (6.15) | 116 (6.84) | | Histology | | | | | | KSCC | 1887 (33.32) | 1329 (33.51) | 558 (32.90) | 0.182 | | DNKC | 1458 (25.75) | 982 (24.75) | 476 (28.07) | | UNKC | 944 (16.67) | 661 (16.66) | 283 (16.68) | | Others | 1374 (24.26) | 995 (25.08) | 379 (22.35) | | Grade | | | | | | Well | 92 (1.62) | 63 (1.59) | 29 (1.71) | 0.762 | | Moderate | 476 (8.41) | 317 (7.99) | 159 (9.38) | | Poor | 1626 (28.71) | 1158 (29.19) | 468 (27.59) | | Undifferentiated | 1571 (27.74) | 1086 (27.38) | 485 (28.6) | | Unknown | 1898 (33.52) | 1343 (33.85) | 555 (32.72) | | Tumor size (cm) | | | | | | <3 | 1085 (19.16) | 754 (19.01) | 331 (19.52) | 0.815 | | 3-5 | 1661 (29.33) | 1173 (29.57) | 488 (28.77) | | >5 | 735 (12.98) | 497 (12.53) | 238 (14.03) | | Unknown | 2182 (38.53) | 1543 (38.89) | 639 (37.68) | | AJCC stage | | | | | | I | 462 (8.16) | 317 (7.99) | 145 (8.55) | 0.997 | | II | 1349 (23.82) | 948 (23.89) | 401 (23.64) | | III | 1789 (31.59) | 1251 (31.54) | 538 (31.72) | | IV | 2063 (36.43) | 1451 (36.58) | 612 (36.09) | | T stage | | | | | | T1 | 1817 (32.09) | 1273 (32.09) | 544 (32.07) | 0.997 | | T2 | 1387 (24.49) | 963 (24.28) | 424 (25.00) | | T3 | 1168 (20.63) | 827 (20.85) | 341 (20.11) | | T4 | 1291 (22.79) | 904 (22.78) | 387 (22.82) | | N stage | | | | | | N0 | 1372 (24.23) | 959 (24.17) | 413 (24.35) | 0.983 | | N1 | 1869 (30.78) | 1313 (33.10) | 556 (32.78) | | N2 | 1743 (30.78) | 1230 (31.01) | 513 (30.25) | | N3 | 679 (11.99) | 465 (11.72) | 214 (12.62) | | M stage | | | | | | M0 | 5245 (92.62) | 3667 (92.44) | 1578 (93.04) | 0.728 | | M1 | 418 (7.38) | 300 (7.56) | 118 (6.96) | | Chemotherapy | | | | | | Yes | 4918 (86.84) | 3448 (86.92) | 1470 (86.67) | 0.970 | | No/unknown | 745 (13.16) | 519 (13.08) | 226 (13.33) |
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