Characterisation of APS-1 Experimental Models Is Crucial for Development of Novel Therapies

Figure 3

TSA expression pattern in Aire^+/+ and Aire^−/− mice. Quantitative PCR analysis of expression of 15 Aire-dependent TSAs and 5 Aire-independent TSAs in thymic cells obtained from 4-week-old Aire^+/+ mice () and Aire^−/− mice (). Results normalised to the expression of β-actin and presented relative to the expression values in Aire^−/− thymic cells. Data were analysed by two-way ANOVA and Sidak’s multiple comparison test. , , and . ± SEM.

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