Characterisation of APS-1 Experimental Models Is Crucial for Development of Novel Therapies

Figure 6

Summary of tissue infiltrate in Aire^+/+ mice and Aire^−/− mice. In 4-week-old mice, no tissue infiltrations were observed in both Aire^+/+ and Aire^-/- mice. In 12-week-old mice, tissues with lymphocytic infiltration highlighted for each Aire^-/- mouse.