Proteomic-Based Discovery of Predictive Biomarkers for Drug Therapy Response and Personalized Medicine in Chronic Immune Thrombocytopenia

Table 2

The list of hubs and bottlenecks and hub-bottlenecks of merged network.

	Gene name	Degree	Betweenness centrality
Hubs
1	APOA1	31	0.36595308
2	TF	23	0.40234675
3	GC	19	0.16563324
4	HP	17	0.13375361
5	FGG	17	0.11910425
6	FGB	15	0.06095966
7	FGA	14	0.05532558
8	APOB	14	0.02554443
Bottlenecks
1	CDC20	4	0.59090909
2	FBXO5	4	0.45454545
3	NUP107	5	0.43181818
4	TF	23	0.40234675
5	APOA1	31	0.36595308
6	SEH1L	5	0.18939394
7	GC	19	0.16563324
8	TUBB3	2	0.13796193
9	HP	17	0.13375361
10	KRT1	11	0.1318414
11	ARHGEF7	2	0.11959686
Hub-bottlenecks
1	APOA1	31	0.36595308
2	TF	23	0.40234675
3	GC	19	0.16563324
4	HP	17	0.13375361