Proteomic-Based Discovery of Predictive Biomarkers for Drug Therapy Response and Personalized Medicine in Chronic Immune Thrombocytopenia

Table 4

The more significant enriched GO analysis of sixteen differentially expressed proteins.

	Category	Term	Count	value	Gene symbol
	Biological process
1	GOTERM_BP_DIRECT	GO:0002576~platelet degranulation	4	9.67-05	FGB, TF, FGG, APOA1
2	GOTERM_BP_DIRECT	GO:0042730~fibrinolysis	3	1.55-04	FGB, KRT1, FGG
3	GOTERM_BP_DIRECT	GO:1900026~positive regulation of substrate adhesion-dependent cell spreading	3	3.64-04	FGB, FGG, APOA1
4	GOTERM_BP_DIRECT	GO:0072378~blood coagulation, fibrin clot formation	2	0.003569	FGB, FGG
5	GOTERM_BP_DIRECT	GO:0051180~vitamin transport	2	0.004459	APOA1, GC
	Cellular component
1	GOTERM_CC_DIRECT	GO:0072562~blood microparticle	7	1.43-09	FGB, TF, KRT1, FGG, HP, APOA1, GC
2	GOTERM_CC_DIRECT	GO:0005615~extracellular space	9	3.51-06	FGB, TF, RBP4, KRT1, FGG, HP, APOA1, KRT10, GC
3	GOTERM_CC_DIRECT	GO:0070062~extracellular exosome	11	1.07-05	FGB, TF, RBP4, KRT27, KRT1, FGG, HP, APOA1, SCRIB, KRT10, GC
4	GOTERM_CC_DIRECT	GO:0005576~extracellular region	7	0.00117	FGB, TF, RBP4, FGG, HP, APOA1, GC
5	GOTERM_CC_DIRECT	GO:0005577~fibrinogen complex	2	0.007385	FGB, FGG
	Molecular function
1	GOTERM_MF_DIRECT	GO:0005198~structural molecule activity	4	1.00-03	FGB, KRT27, KRT1, FGG
2	GOTERM_MF_DIRECT	GO:0005515~protein binding	12	0.0401263	FGB, DYRK4, TF, RBP4, SEH1L, KRT1, FGG, HP, ZFP69B, APOA1, SCRIB, FBXO5